TOFACITINIB CITRATE
Chemical Name | Tofacitinib citrate |
CAS Number | 540737-29-9 |
Molecular Formula | C16H20N6O.C6H8O7 |
Molecular Weight | 504.50 |
Molecular Structure | |
Storage | Kept in dry and cool place, avoid of sunlight |
Application | Treat rheumatoid arthrists. |
SPECIFICATION
Items | Specification |
Appearance | Yellow to brown oil |
Identification | A.IR: similar to Reference Substance |
B.Retention Time: similar to Reference Substance | |
Loss on Drying | ≤0.5% |
Related Substances | Acetyl impurity≤0.15% |
Chloroacetyl impurity≤0.15% | |
Diastereomer≤0.15% | |
Single impurity≤0.10% | |
Total impurities≤1.0% | |
Enantiomer | ≤0.15% |
Residue solvents | Residue solvents |
Toluene≤890ppm | |
Ethanol≤5000ppm | |
Acetone≤5000ppm | |
Dichloromethane≤600ppm | |
Ethyl acetate≤5000ppm | |
Hxaene≤290ppm | |
Assay | 98.0~102.0% |